With the desire to fully understand the use of drugs in the treatment of ischemic stroke to improve treatment effectiveness as well as safety for patients, the article presents the results of research on drug use characteristics and comments on the results of cerebral infarction treatment at the Stroke Center of Nghe An General Hospital. 113 medical records of infarction patients treated at the Stroke Center of Nghe An General Hospital from January 1, 2023 to June 30, 2023 were researched and analyzed. The results showed that thrombolytic therapy was consistent with the guidelines, most patients were stable and discharged from the hospital, and 6 adverse events were recorded, including 4 bleeding, 1 increased intracranial pressure, and 1 seizure.