The study was carried out from September to December 2022. The purpose of the study was to investigate the effect of parasites on fish survival and effective treatment solution. Fresh scanning method was applied to detect parasites and fish infected with parasites were bathed with fresh water supplemented with Formalin (150ppm) for 7-9 minutes/time, combined with the addition of 20mL Fishcare (extract of cinnamon and garlic) in 1 quintal of fish feed for 7 consecutive days. The results indicated: Amyloodinium sp. and Cryptocaryon sp. parasites in golden fin pompano with infection intensity of 13.1 and 21.6 parasites/field, respectively. Abnormal clinical signs were noted including decreased feeding, swimming close to the cage wall, pale gills, uneven body color. Methods of bathing fish, changing cages, supplementing with herbs extracted from cinnamon and garlic showed effective treatmentwith survival rate of over 90%. This is the first fully detailed report on the effect of Amyloodinium sp. and Cryptocaryon sp on the survival rate of golden fin pompano and the treatment techniques of these two parasite species.