Fissistigma is one of the largest genera in the family Annonaceae, comprising approximately 75 species. Fissistigma kwangsiense Tsiang & P. T. Li (Annonaceae), a new record for the flora of Vietnam, was described and illustrated from Pu Hoat and Pu Huong Nature Resever, Pu Mat National Park, Nghe An Province. The specimens are preserved in the Herbarium of the Institute of Ecology and Biological Resources (HN) and Vinh University, Vietnam. Data on distribution, ecology and phenology of F. kwangsiense are provided