This article refers to the application of artificial intelligence to design digital learning resources in teaching history in high schools. Through theoretical research methods, the article has synthesized information from domestic and foreign books, newspapers, and reference materials on artificial intelligence, digital learning materials, and flipped classrooms to determine the relationship and importance of applying artificial intelligence to design digital learning resources in teaching history in high schools. From there, the article proposes measures and procedures for applying artificial intelligence to design e-Learning lessons, cartoons, and historical comics, contributing to improving students’ self-study efficiency in the out-of-class learning stage of the flipped classroom model, implementing the policy of fundamental and comprehensive innovation of the current Vietnamese education system.