According to the General Education Program 2018, it is determined that self-study and informatics competencies are two of the core competencies that need to be formed and developed for high school students. Developing chemistry knowledge search software with open source to help teachers and students update their knowledge in addition to the available knowledge is also a way to help students study effectively by themselves. With the design process from basic theory, application exercises, guided practice, and testing to assessing self-study results will help teachers and students implement the self-study process smoothly. The results of the pedagogical experiment show that the content and technical impacts of the software have fostered the chemistry self-study competence for high school students