A phytochemical study of extracts of Uvaria boniana Fin. & Gagnep collected at Pu Mat National Park, Nghe An Province leaves led to the isolation of three secondary metabolites, including 6-methoxyzeylenol (1), aristolactam AII (2), and stigmasta-4,22-dien-3-on (3). Their structure elucidation was determined on the basis of one and two-dimensional NMR and other spectrometric methods. This is the first report on the chemical constituents of Vietnamese Uvaria boniana.