The microsporidian parasite (Enterocytozoon hepatopenaei - EHP) causes disease related to slow growth in the brackish water shrimp. The disease is determined to be transmitted both vertically (from broodstock to offspring) and horizontally (from infected individuals to heathy ones). This paper reviewed informations from both national and international publications reporting to the EHP cariers which could transmitte EHP to shrimp and some factors that affect EHP disease. The results showed that 15 species could be EHP carriers; those were shrimp (5 species), zooplankton (04 species), crab, eggs shrimps, small shrimps, snail, oysters and polychaete (1 species). EHP has been reported to exist in water, pond bottom and shrimp feces where there was not the present of host or carrier cell. Several factors affecting EHP have been recorded including farming season, age of shrimp, species of shrimp and white feces syndrome.